The Regenerative Institute at CROM (RIC) is Denver’s premiere Stem Cell Therapy and Regenerative Medicine group. Regenerative Medicine includes Stem Cell Therapy, Platelet Rich Plasma (PRP), Adipose Tissue and Amniotic Allograft. These therapies can be of great benefit for athletic injuries and age-related conditions such as arthritis. Stem Cell Therapy and other Regenerative Therapies that RIC performs may be an alternative to surgery for certain types of orthopedic conditions including of joints, muscles, tendons and ligaments. Regenerative Therapies have the potential to provide pain relief, allowing you to decrease or stop the use of pain medications. If Regenerative Medicine isn't your best option, RIC also preforms a variety of other effective musculoskeletal treatments.

Why we are the best:

The Most Comprehensive Treatments

At RIC we don't perform or endorse a single type of Stem Cell Therapy, rather we offer a variety of the best Regenerative treatments available. This allows us to use the most efficacious type of treatment for your injury, and what is most compatible with your physiology. For example, we commonly use your own Bone Marrow Aspirate Concentrate (BMAC) as a source of stem cells, or Platelet Rich Plasma (PRP). However, the vitality of your own tissues from these sources may be reduced if you have diminished health, advanced age, or take certain medications. In that case we can offer other sources of Regenerative Therapies that may work better such as Amniotic Allograft or Umbilical Cord Blood. Because we perform a myriad of other musculoskeletal treatments, we'll advise you if other procedures exist for your condition, be they less expensive or better options. After your Stem Cell procedure we can provide a network of dietary, psychological, exercise and physical therapy guidance to optimize the healing process.

Extensive Training

The Regenerative Institute at CROM's physicians are Board Certified doctors in Physical Medicine & Rehabilitation (PM&R), meaning that we specialize in diagnosing and treating non-operative orthopedic injuries. This makes us uniquely qualified to perform Regenerative Therapies including Stem Cell Therapy and PRP injections, where it's critical to accurately diagnose to be able to provide precise treatment, followed by a tailored recovery protocol. We are not general physicians or non-medical practitioners who have superficially learned Regenerative Medicine. RIC physicians have been performing musculoskeletal treatments since 1992.

Imaging Guidance

Some practitioners perform Regenerative Medicine injections without imaging (also called "blind" injections), and may also attempt to identify your injury without diagnostic imaging. Regenerative Medicine injections should always be guided with imaging. At the Regenerative Institute at CROM, we use live ultrasound imaging or fluoroscopic imaging (also call "live x-ray") for precise Stem Cell and PRP procedures depending upon the needs required for the specific procedure. Ultrasound imaging is a safe, real-time means to view your anatomy and can be used to compare pre and post procedure progress.

Competitive Pricing

Stem Cell Therapy and other Regenerative Medicine procedures can help people to heal without surgery, and we think that shouldn't be prohibitively expensive. Because Regenerative Medicine typically is not covered by insurance, we offer competitive self-pay pricing for our Stem Cell Therapy and PRP procedures. With current trends in healthcare coverage, our procedures may cost less than your deductible. Contact us to find out more.

Areas and Conditions Treated

Contact us to determine if you are a candidate for Stem Cell Therapy/Regenerative Medicine. RIC has 2 Denver offices; Aurora and Greenwood Village. You can schedule an exam to diagnose your condition and discuss whether Stem Cell Therapy or PRP would be more effective, and provide guidance for other treatments if Regenerative Medicine is not the best option. Procedures take about an hour in-office, or in some cases at a surgery center. You go home the same day. Following the Regenerative Medicine procedure you will be instructed on a recovery protocol.

Regenerative Medicine FAQ's

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What is Stem Cell Therapy?

Sometimes injured areas of the body need extra help to "restart" and invigorate a stuck or stopped healing process. Tissue that contain stem cells can be injected to the injured area. Stem cells have the ability to locate, and move towards the damaged tissue. Once there, they release biological signals that stimulate your own body's healing process. This biological activity reduces inflammation and encourages the body to build up healthy tissue. The stem cells have the capability of differentiating into bone, cartilage, muscle, and ligament tissues. Stem Cell Therapy may heal many types of injuries that may have required surgery in the past such as partial thickness muscle tears or degenerative joints. The stem cells used at the RIC follow the FDA criteria for homologous use and are minimally manipulated.

What is PRP (Platelet Rich Plasma)?

Platelet Rich Plasma (PRP) is a regenerative therapy that is obtained from your own body. Platelets are components of the the blood that start the healing process after an injury; for example, when someone cuts their arm, the platelets stop the bleeding and then release signals to the body to begin the healing process. This natural process is harnessed with PRP therapy. A volume of your blood is simply extracted from your arm and the platelets from this blood are then concentrated to make PRP. The PRP is then injected to the site of injury. These platelets contain a multitude of growth factors that can help heal damaged tissue, including stimulating the local stem cells in your tissue to help heal your injury. PRP may be a more affordable option for people interested in regenerative therapies.

Where do RIC's Stem Cells Come from?

Several sources of Regenerative Therapies are available, and RIC will help you determine the right therapy based on your specific condition. Stem Cells from Bone Marrow Aspirate are the primary source of Stem Cells used by RIC. However, other tissues may offer advantages depending upon your health, age, and the medications that you use. Your RIC doctor may recommend a Regenerative Therapy from another source such as Adipose (your own fat) or Amniotic tissue or Umbilical Cord Blood, of which these latter two come from healthy, screened donors.

Are Stem Cells Ethical?

Yes! RIC's Stem Cell therapy does not involve harvesting cells from embryos. We harvest tissue that contains stem cells either from your own body, or tissue from screened, healthy donors.

The stem cells used at the RIC follow the FDA criteria for homologous use and are minimally manipulated.

How many Regenerative Treatments will I need?

RIC's goal is to treat specific injuries with a single treatment. We want to be as effective as possible with one treatment, and minimize unnecessary cost to you. However, some cases can be quite challenging, and depending on factors such as severity of your pain, severity of the problem, your age, and area that is being treated, additional processes may be considered.

What should I expect from the Procedure?

Peripheral joint procedures (e.g shoulder, elbow, wrist/hand, hip, knee, ankle/foot) are typically performed in office and take about an hour. Spine procedures are performed in a surgery center, and you can go home the same day.

Typically a medical exam will be performed prior to a procedure, including reviewing the history of your condition, performing a physical exam, and reviewing related imaging studies to provide a specific diagnosis for the most precise treatment. Your problem area will then receive the Regenerative Medicine injection under imaging guidance. If an autologous graft is used (i.e. tissue from your own body), this will first be drawn from your body and processed following FDA regulations of minimal manipulation.

Following your procedure you will be given a post-Regenerative Medicine protocol, as determined by your physician, to optimize your healing and guide you recovery. Some patients may require modified weight-bearing restrictions for a week or two, depending on the procedure and your phyisician's recommendations.